Borys Hrinczenko, MD

Borys  Hrinczenko
  • Professor
  • Director, Hematology and Oncology Fellowship Program
  • Division of Hematology and Oncology
  • -
  • Clinician at Karmanos Cancer Institute at McLaren Greater Lansing
  • Clinic Address: Karmanos Cancer Institute of McLaren Greater Lansing, 3520 Forest Road, Lansing, MI 48910
  • Clinic Phone: 517-975-9500
  • Academic Address: 788 Service Road, B412 Clinical Center
  • Academic Phone: 517-353-3128

Academic Support Staff: Beth Moore

For clinical appointments and patient-care questions: please contact Karmanos Cancer Institute of McLaren Greater Lansing at (517) 975-9500


My main interest is in new therapies for lung cancer, including the use of immune checkpoint inhibitors, the same treatments for which James P. Allison and Tasuku Honjo were awarded the 2018 Nobel Prize in Medicine. At the Breslin Cancer Center, we have Phase I clinical trials using checkpoint inhibitors to harness the body’s immune system against lung cancer. I’m collaborating on other projects with several MSU researchers, including:
  • Chemistry Professor Greg Swain, who is developing a device to measure nitric oxide and peroxynitrite in exhaled breath to determine if these are biomarkers for lung cancer.
  • Physiology Professor Eran Andrechek, who discovered in a preclinical model that some lung cancer patients with an overlooked mutation might respond well to treatment with tyrosine kinase inhibitors.
  • Pharmacology and Toxicology Associate Professor Karen Liby, who is studying rexinoid drugs for potentially treating lung cancer patients who have the KRAS mutation.
  • Bryan R. Smith, an associate professor of biomedical engineering, who is interested in using nanotechnology to reverse immunosuppression in lung cancer.

These are just a few examples of how we at MSU are collaborating across many disciplines to fight this devastating disease.


Medical School: SUNY Downstate, Brooklyn, New York
Residency: Mayo Graduate School of Medicine, Rochester, Minnesota
Fellowship: Clinical-National Institutes of Health, NHLBI, Hematology Branch, Bethesda, Maryland
Fellowship: Research-National Institutes of Health, NIDDK, Laboratory of Chemical Biology, Bethesda, Maryland


  • American Board of Internal Medicine
  • Hematology Subspecialty
  • Oncology Subspecialty


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Hrinczenko B[Author]